Synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) via multi-component reactions by using silica-bonded sulfamic acid derivatives

نویسندگان

  • Khodabakhsh Niknam Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr 75169 Iran.
  • Shekoofeh Tayebi Young Researchers Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran.
چکیده مقاله:

The one-pot, multi-component synthesis of 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) by tandem Knoevenagel-Michael reaction of phenylhydrazine, ethyl acetoacetate and aldehydes in the presence of silica-bonded N-propylpiperazine sulfamic acid (SBPPSA) as a recyclable solid acid catalyst was reported. SBPPSA showed much the same efficiency when used in consecutive reaction runs.

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منابع مشابه

synthesis of 4,4′-(arylmethylene)bis(1h-pyrazol-5-ols) via multi-component reactions by using silica-bonded sulfamic acid derivatives

the one-pot, multi-component synthesis of 4,4′-(arylmethylene)bis(1h-pyrazol-5-ols) by tandem knoevenagel-michael reaction of phenylhydrazine, ethyl acetoacetate and aldehydes in the presence of silica-bonded n-propylpiperazine sulfamic acid (sbppsa) as a recyclable solid acid catalyst was reported. sbppsa showed much the same efficiency when used in consecutive reaction runs.

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Reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields.

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silica-bonded n-propyldiethylenetriamine sulfamic acid as a recyclable solid acid catalyst for the synthesis of coumarin and biscoumarin derivatives

silica-bonded n-propyldiethylenetriamine sulfamic acid (sbpdsa) was found as an efficient solid acid for the synthesis of coumarins. coumarin derivatives were obtained via the pechmann condensation reaction of phenols and β-keto-esters at 80 oc under solvent-free conditions. also, biscoumarins were obtained via the condensation of aldehydes and 4-hydroxycoumarin in water at reflux conditions. t...

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عنوان ژورنال

دوره 2  شماره 2

صفحات  69- 74

تاریخ انتشار 2012-06-01

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